Drug Discovery and Development

Transforming data into defensible leads with computational and genomic foresight.

In Silico & Computational Chemistry Advisory:
AI-driven molecular docking, virtual screening, and predictive ADME/Tox to de-risk capital allocation pre-synthesis.

Discovery & Medicinal Chemistry:
Hit-to-lead (H2L), SAR studies, and scaffold hopping to strengthen non-infringing IP portfolios for both Small Molecules and Complex Peptides.

Discovery Biology & Screening:
Independent vetting of labs for assay reproducibility to eliminate systemic discovery failure in High-Potency and Large Molecule programs.

Genomic Target Identification:
Specialized oversight for Precision Medicine platforms, ensuring data integrity in biomarker discovery and genetic target validation.

Pre-formulation, formulation and Pre-clinical studies

Ensuring technical fidelity across complex synthetic and biological modalities.

Process Chemistry & Route Development:
Design of cost-effective, ESG-compliant ("Green") synthetic routes and impurity profiling for HPAPI (OEB 4/5/6) and Nucleic Acid Therapies.

CMC & Formulation Excellence:
Solubility enhancement for BCS Class II/IV molecules and conjugation stability for ADCs, PDCs, and RDCs.

Advanced Modality Scale-up:
Technical governance for mAbs, Recombinant Proteins, and mRNA platforms, focusing on cell-line fidelity and analytical biosimilarity (QbD).

Preclinical & IND-Enabling Oversight:
Management of GLP-compliant toxicology and bioanalytical packages engineered for FDA/EMA/PMDA acceptance.

Clinical & Regulatory Governanace

Navigating the "Last Mile" to market with absolute data integrity.

Clinical Trials & Bioanalytical Oversight:
Site selection and monitoring for BA/BE and Phase I/II studies, specializing in Cold-Chain logistics for Cell & Gene Therapy (CGT).

Regulatory & Quality Advisory:
eCTD dossier preparation, ALCOA+ data integrity audits, and mock inspections for global compliance.

Precision Medicine Access:
Advisory on Companion Diagnostics (CDx) and genomic data governance for targeted oncology frontiers.

Virtual COO Services:
Serving as your dedicated Asia operations lead for milestone tracking and multi-vendor coordination.